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Flooding caused by Storm Christoph is threatening a factory manufacturing the Oxford Covid vaccine.
Emergency services were dispatched to the scene in Wrexham, Wales, in the early hours of this morning.
Fire crews have been pumping water from the area and clearing gullies to make sure water doesn't build up.
Up to 30 people in Bangor-on-Dee, Wrexham, were evacuated after a severe flood warning was issued – with a major incident declared.
The River Dee, which runs through the village, was at its highest level since the water gauge became operational in 1996 – rising to 16.45m (54 ft).
Wrexham County Borough Council leader Mark Pritchard told BBC Radio Wales: "We had an incident at Wrexham Industrial Estate, the Oxford vaccination is produced there and the warehouse where it is stored, obviously I can't tell you where it is, but we had to work in partnership to make sure we didn't lose the vaccinations in the floods.
"I've been up all night…it's a very difficult time for us."
A multi-agency statement read: "As a severe weather warning indicates that there is a risk to life, it was deemed necessary to evacuate residents of Bangor-on-Dee, in order to ensure the ongoing safety of the community.
"The evacuation effort continues, with all routes in and out of the village currently closed to the public due to the flooding."
Natural Resources Wales has issued 34 other flood warnings and 47 alerts.
One man was rescued from the roof of his car after it was swept away in raging floodwater, North Wales Live reports.
The motorist was trying to ford a flooded road between Llandegai and Bangor, north Wales, when his car was swept away.
The vehicle was trapped in deeper waters, but the driver managed to clamber onto the roof and call emergency services.
Almost 200 flood warnings remained in place across England on Thursday morning, January 22, with four "severe" warnings – meaning danger to life – issued for the North West.
Residents in East Didsbury, West Didsbury and Northenden areas of Greater Manchester were told to leave their homes on Wednesday night because of rising water levels, the city council said.
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